Figure 9

Damaged endothelial cells (TUNEL+ GS-IB4+) (A), proliferating endothelial cells (PCNA+ GS-IB4+) (B), proliferating and activated mesangial cells (PCNA+ α-actin+) (C), α-actin+ activated mesangial areas (μm2) (D), glomerular hypertrophy (glomerular tuft area: μm2) (E), and areas of accumulation of mesangial matrix (μm2) (F) in the progression (•; n = 4), the recovery (□ n = 4), and the pretolerized control (□; n = 2) groups. A, Values are expressed as mean ± sem. B to F, Values are expressed as mean ± sd. * p < 0.05, ** p < 0.01, *** p < 0.001.