Table 1 Expression of α-Catenin in Familial and Sporadic Colorectal Neoplams as Compared with the Adjacent Non-Neoplastic Mucosa
From: Variable Nuclear Localization of α-Catenin in Colorectal Carcinoma
Tumors | Membrane | Cytoplasm | Nucleus | |||
|---|---|---|---|---|---|---|
Preserved | Decreased | Normal | Increased | Absent | Present | |
Adenomas from FAP patients | 20/20 | 0/20 | 0/20 | 20/20 | 20/20 | 0/20 |
Sporadic adenomas | 14/15 | 1/15 | 2/15 | 13/15 | 15/15 | 0/15 |
Carcinomas from FAP patients | 4/5 | 1/5 | 0/5 | 5/5 | 4/5 | 1/5 |
Sporadic carcinomas | 18/30 | 12/30 | 3/30 | 27/30 | 29/30 | 1/30 |