Table 1 Summary of the Results of TFF1 PCR/SSCP Screening in a Series of 90 Gastric Carcinoma Cases

From: Loss of Heterozygosity and Promoter Methylation, but not Mutation, May Underlie Loss of TFF1 in Gastric Carcinoma

Location

Nucleotide changea

Predicted protein change

Frequency (%)

5′ UTR

−2C→T

–

35/90 (38.9)

Exon 1

73G→A

E25K (missense)

4/90 (4.4)

Intron 1

85 + 8G→A

–

49/90 (54.4)

3′ UTR

255 + 29T→C

–

1/90 (1.1)

3′ UTR

255 + 33G→A

–

1/90 (1.1)

3′ UTR

255 + 41G→A

–

6/90 (6.7)

  1. aNumbering is according to the cDNA starting at A in start codon (GenBank Accession No. AB038162).
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