Figure 1

Human decay-accelerating factor (HDAF) and the DAF-Fc molecules. DAF is made up of the four short consensus repeat (SCR) sequences, an S/T region, and a glycosylphosphatidylinositol (GPI) anchor. The dimeric DAF-Fc molecule contains two to four SRC sequence regions ligated to the hinge and Fc portion of a human IgG antibody.