Figure 2 | Laboratory Investigation

Figure 2

From: Possible Involvement of Keratinocyte Growth Factor and Its Receptor in Enhanced Epithelial-Cell Proliferation and Acquired Recurrence of Middle-Ear Cholesteatoma

Figure 2

Immunohistochemical detection of KGF and KGFR in paraffin sections of middle-ear cholesteatoma. A, Immunohistochemistry using anti-KGF antibody. Note the presence of KGF-positive cells in the stroma. B, Competition assay on serial sections by adding excess amount of 8–1 synthetic peptide (500-fold molar excess). C, Immunohistochemistry using anti-KGFR serum. Note the presence of KGFR-positive cells in the epithelium. D, Competition assay on serial sections by adding excess amount of 10–1 synthetic peptide (500-fold molar excess). Asterisks indicate the same lesion in the serial sections. Magnification, × 175.

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