Figure 2 | Laboratory Investigation

Figure 2

From: The Myofibroblastic Conversion of Peribiliary Fibrogenic Cells Distinct from Hepatic Stellate Cells Is Stimulated by Platelet-Derived Growth Factor During Liver Fibrogenesis

Figure 2

Hepatic stellate cells (HSC) and bile duct segments are mutually exclusive in cell isolates. Freshly isolated HSC identified (A) under light microscopy, exhibit (B) a characteristic autofluorescence under UV excitation at 328-nm wavelength. Bile duct segment 24 hours after plating shows fibroblast-like cells outgrowing from the periphery (arrowheads) (C) under light microscopy and no fluorescence (D) under UV excitation, demonstrating the absence of HSC in the preparation. Original magnification: A to D, × 400.

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