Figure 2

Liver stem cell factor (SCF) levels in mice treated with lethal (300 mg/kg) or sublethal (200 mg/kg) doses of acetaminophen. A portion of the liver from killed mice was taken and weighed immediately after extraction at various time points after acetaminophen administration. The liver tissue was ground in PBS with 0.1% Triton X-100 containing anti-proteases, and the cell-free supernatant was assayed in an SCF-specific enzyme-linked immunosorbent assay (ELISA). The data represent mean ± se from at least six mice per time point; *p = 0.05.