Figure 8
From: Stem Cell Factor Attenuates Liver Damage in a Murine Model of Acetaminophen-Induced Hepatic Injury
SCF inhibits acetaminophen-induced cytochrome P450 cyp2E1 in livers of challenged mice. Animals were treated with 1 μg of recombinant SCF or saline within 30 minutes of acetaminophen administration (300 mg/kg). Livers were harvested at 1 and 4 hours after acetaminophen challenge to examine the early P450 cyp2E1 expression by RT-PCR analysis. Data are representative of expression in three to four mice per group.
