Figure 5

Immunohistochemistry for Fas in control and NODscid pancreata during the early postnatal period. A to C, 3-day-old NOD (A, × 500), NODscid (B, × 500), and control C57BL/6 (C, × 800) mouse pancreata. Note the Fas positivity in nerve-like structures localized near or around islets and ducts in all strains. D to F, 1-week-old NOD (D), NODscid (E), and DBA/2 (F) mouse pancreata (× 800). Fas+ nerve-like structures are present at the ductular pole of the islet, around the islet and acini. G to I, 4-week-old NOD (G, × 320), NODscid (H, × 500), and control C57BL/6 (I, × 500) mouse pancreata. Fas+ nerve-like structures are still present at the periphery of vessels, ducts, and islets in all strains.