Figure 6 | Laboratory Investigation

Figure 6

From: Proapoptosis and Antiapoptosis-Related Molecules During Postnatal Pancreas Development in Control and Nonobese Diabetic Mice: Relationship with Innervation

Figure 6

Immunohistochemistry for Bcl-2 in control and NODscid pancreata during the early postnatal period. A to C, 3-day-old NOD (A, × 200), NODscid (B, × 500), and control C57BL/6 (C, × 500) pancreata. Note the numerous Bcl-2+ structures scattered in the exocrine tissue in NOD and NODscid pancreata and the less abundant Bcl-2 nerve-like structures in control mice (C). D to F, 4-week-old NOD pancreata (× 200). Numerous Bcl-2+ structures are scattered in the exocrine tissue and septa and at the periphery of vessels and ducts (D and E); F, a serial section of (E) is the negative control. G to I, 4-week-old control DBA/2 (G and H, × 200 and × 500, respectively) and C57BL/6 (I, × 200) pancreata. Rare and fine nerve-like structures are present in some but not all sections, unlike what was observed in NOD mice (D and E).

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