Figure 7

Immunohistochemical staining of RhoA in epithelial ovarian tumors. The specific staining for RhoA was observed in the cytoplasm of the tumor cells. The immunostaining of RhoA was negative in benign tumor such as serous (a) and mucinous (b) cystadenomas and weak in borderline malignant tumors (c). There were a few cases of serous borderline tumor showing moderate immunostaining for RhoA (d). In contrast, moderate or strong immunostaining for RhoA was frequently observed in ovarian carcinomas of serous (e), mucinous (f), endometrioid (g), and clear cell (h) histology. Original magnification, ×200.