Figure 4

Immunohistochemical staining of TSLC1 in pulmonary adenocarcinomas. Sections of BAC (Case 15; A and B), papillary adenocarcinoma (Case 17; C and D), and adenocarcinoma with mixed subtypes (Cases 38 and 43; E and F) were reacted with the anti-TSLC1 antibody and colored with aminoethylcarbazole. All sections were counterstained with hematoxylin. B and D show high-power field images of the areas encircled by bold lines in A and C. Note that TSLC1 signals are detectable in the left half (corresponding to the lepidic growth component) but not in the right half (corresponding to the papillary component) of papillary adenocarcinoma (Case 17). Original magnification: A (Ă— 100); B, D, E, and F (Ă— 400); and C (Ă— 40).