Figure 2
(A and B) Primary posterior cervical tumor, 1991 (See also Fig. 1A). (A) Cellular areas of tumor growing in fascicular pattern are intermixed with scar-like fibrosis (hematoxylin eosin). (B) Large myofibroblastic cells with vesicular nuclei and prominent nucleoli are embedded in collagenous matrix and intermixed with inflammatory cells (hematoxylin eosin). (C) Peripheral portion of the myofibroblast shows abundant intermediate filaments, dense bodies (arrowheads), and attachment plaques (arrow) (electron microscopy). (D) Right-middle lobe nodule, 1996 (See also Fig. 1B2). The lesion shows scar-like fibrosis as well as cellular areas. Prominent inflammatory infiltrate is present at the periphery (hematoxylin eosin). (E to H) Recurrent metastatic central lung mass, 2002 (See also Fig. 1C2). (E) Strong cytoplasmic staining for anaplastic lymphoma kinase (immunohistochemistry). (F) Microscopic areas of tumor necrosis (hematoxylin eosin). (G) Tumor infiltrating small bronchus (hematoxylin eosin). (H) Tumor invading into a small-to-intermediate caliber intrapulmonary artery at the periphery of the mass (Van Gieson stain).
