Figure 5 | Laboratory Investigation

Figure 5

From: Renal Damage in the SHR/N-cp Type 2 Diabetes Model: Comparison of an Angiotensin-Converting Enzyme Inhibitor and Endothelin Receptor Blocker

Figure 5

Effect of ACE-i and ETA-RB on endothelin protein expression of glomerular cells (immunohistochemistry, magnification, 1:300). A, Marked staining of glomerular cells in untreated diabetic obese animal. B, No staining in nondiabetic untreated lean animal. C, ETA-RB treatment in obese diabetic rats still led to marked staining of glomerular cells. D, Only very little staining in glomerular cells of ACE-i–treated obese diabetic rats.

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