Table 1 Animal Data (at the End of the Experiment)

From: Renal Damage in the SHR/N-cp Type 2 Diabetes Model: Comparison of an Angiotensin-Converting Enzyme Inhibitor and Endothelin Receptor Blocker

Animal group

Body weight (g)

Kidney weight (g)

Blood glucose (mg/dl)

Systolic blood pressure (mmHg)

Urinary albumin excretion (mg/24 h)

Nondiabetic SHR/N-cp (n = 9)

489 ± 41*†‡

2.01 ± 0.21

99 ± 4.8*†‡

144 ± 31

33 ± 14*

Nondiabetic SHR/N-cp + ETA-RB (n = 8)

418 ± 34*†‡

1.4 ± 0.24‡

101 ± 11.0*†‡

152 ± 45

15 ± 7.8*‡

Nondiabetic SHR/N-cp + ACE-i (n = 13)

496 ± 74*†‡

1.54 ± 0.29+*‡

87 ± 17*†‡

133 ± 27*

7.8 ± 4.2*†‡

Diabetic SHR/N-cp (n = 7)

660 ± 68

2.27 ± 0.21

378 ± 58.7

154 ± 19†

177 ± 77†

Diabetic SHR/N-cp + ETA-RB (n = 9)

650 ± 57

1.9 ± 0.31

386 ± 77

149 ± 22

67 ± 39*

Diabetic SHR/N-cp + ACE-i (n = 12)

627 ± 75

1.91 ± 0.22

316 ± 104

132 ± 34*

48 ± 28*

ANOVA

p < 0.05

p < 0.05

p < 0.05

p < 0.05

p < 0.05

  1. *p < 0.05 vs diabetic SHR/N-cp.
  2. †p < 0.05 vs diabetic SHR/N-cp + ACE-i.
  3. ‡p < 0.05 vs nondiabetic SHR/N-cp + ETA-RB.
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