Table 4 Number of PCNA-Positive Glomerular and Tubulointerstitial Cells

From: Renal Damage in the SHR/N-cp Type 2 Diabetes Model: Comparison of an Angiotensin-Converting Enzyme Inhibitor and Endothelin Receptor Blocker

Animal group

PCNA + cells/glomerular profile

PCNA + cells/ tubulointerstitial area

Nondiabetic SHR/N-cp (n = 9)

1.78 ± 0.89

1.05 ± 1.01

Nondiabetic SHR/N-cp + ETA-RB (n = 8)

2.11 ± 0.16

1.65 ± 0.44

Nondiabetic SHR/N-cp + ACE-i (n = 13)

2.16 ± 0.69

0.97 ± 0.27

Diabetic SHR/N-cp (n = 7)

4.88 ± 1.74*†

4.12 ± 1.06*†

Diabetic SHR/N-cp + ETA-RB (n = 9)

2.67 ± 1.21

2.68 ± 1.08*

Diabetic SHR/N-cp + ACE-i (n = 12)

1.86 ± 0.37

0.45 ± 0.19

ANOVA

p < 0.05

p < 0.05

  1. *p < 0.05 vs nondiabetic SHR/N-cp.
  2. †p < 0.05 vs diabetic SHR/N-cp + ACE-i.
Back to article page