Figure 3 | Laboratory Investigation

Figure 3

From: Monoclonal Expansion with Integration of High-Risk Type Human Papillomaviruses Is an Initial Step for Cervical Carcinogenesis: Association of Clonal Status and Human Papillomavirus Infection with Clinical Outcome in Cervical Intraepithelial Neoplasia

Figure 3

Change in clonality and HPV-16 physical status in a case of progression of CIN (Case 1). Initial CIN1 lesion was polyclonal in composition and contained HPV-16 in episomal form. Twenty-four months later, this lesion progressed to CIN3, which was monoclonal and contained HPV-16 in the mixed type of integrated and episomal forms.

Back to article page