Figure 1 | Laboratory Investigation

Figure 1

From: Potent Phagocytic Activity Discriminates Metastatic and Primary Human Malignant Melanomas: A Key Role of Ezrin

Figure 1

In vivo autophagocytosis in melanoma tumors. A, Histologic preparation of a metastatic melanoma sample. A large epithelioid tumor cell contains an (apparently) intact tumor cell (arrow). The nuclear features of the “ingested” cell are the same as those present in the rest of the sample. [Hematoxylin and eosin (HE): magnification, × 350]. B, Histologic preparation of a metastatic melanoma sample. In the center of the field, a Tunel-positive (apoptotic) cell within a bigger, Tunel-negative cell is shown. (HE: magnification, × 350).

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