Figure 6 | Laboratory Investigation

Figure 6

From: Potent Phagocytic Activity Discriminates Metastatic and Primary Human Malignant Melanomas: A Key Role of Ezrin

Figure 6

Melanoma cell phagocytic activity against yeast cells as evaluated by FACS. Row A, Physic parameters and red fluorescence emission of Congo Red-stained yeast particles and unstained melanoma cells. Row B, Analysis of cell fluorescence emission, performed only in the cells included in region R1 to exclude yeast particles not associated with melanoma cells. Numbers reported in the figure represent the percentage of two melanoma cell lines derived from metastatic lesions (M mel), two melanoma cell lines derived from primary lesions (P mel), and human primary macrophages (macrophages) as positive controls, containing the Congo Red-stained yeast particles.

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