Figure 2
From: Amyloidosis Modifier Genes in the Less Amyloidogenic A/J Mouse Strain
Amyloid index (AI) in SAMP1 and A/J mice and their hybrids and distribution of AI in intercrossed and backcrossed hybrid mice. A, Amyloid deposits in 12-month-old A/J and SAMP1 mice and their hybrids. The AI was determined as the average of the grade of amyloid deposits in five organs (liver, spleen, skin, heart, and stomach). B, AI distribution in 54 intercrossed (A/J × SAMP1)F2 mice. C, AI distribution in 76 backcrossed (A/J × SAMP1) × A/J mice. Bars indicate the number of mice used for the genome scan at matched AI levels.
