Figure 8
From: Attenuated Cerulein-Induced Pancreatitis in Nuclear Factor–κB–Deficient Mice
(A) Representative cerulein (CER)-injected pancreas harvested from a wild-type mouse. Edema: inflammatory cell infiltrates of both interlobular and intralobular interstitium are present (Original magnification, × 25). (B) Representative CER-injected pancreas harvested from a wild-type mouse. Presence of dark bodies showing apoptotic cells engulfed by acinar cells (arrow) (Original magnification × 100). (C) Representative CER-injected pancreas obtained from a nuclear factor–κB knockout mouse. Significant reduction in the edema and in the inflammatory cell infiltrates (Original magnification, × 25). (D) Representative CER-injected pancreas obtained from a nuclear factor–κB knockout mouse. The edema is minimal, and the presence of vacuoles is rare. (Original magnification, × 100).
