Figure 3

Immunohistochemical expression of adipocyte-derived leucine aminopeptidase (A, C, and E) and placental leucine aminopeptidase (B, D, and F) in choriocarcinoma tissues. (A and B) Noninvasive lesions of uterine choriocarcinoma. (C and D) Choriocarcinoma invading the myometrium and stromal vessels. (E and F) Lung metastasis lesions showing invasion into alveolar tissues. Both aminopeptidases were predominantly expressed in invading intermediate-type choriocarcinoma cells. Alv = alveolar tissues; V = vessels. Original magnifications: × 200 (A, B, E, and F) and × 100 (C and D).