Figure 4

Rescue of reduced SHP1 protein expression by 5AzaCdR treatment. Western blot analysis of SHP1 protein in cell lines with or without demethylating reagent 5AzaCdR. Cell lines used were an ATL patient-derived (MT1), B-ALL (KW), Hodgkin’s disease (HDLM2 and L428), and multiple myeloma (U266 and MOLP2) cell lines. −, without treatment; +, with treatment.