Figure 3 | Laboratory Investigation

Figure 3

From: VEGF121 and VEGF165 Regulate Blood Vessel Diameter Through Vascular Endothelial Growth Factor Receptor 2 in an in vitro Angiogenesis Model

Figure 3

Concentration of VEGF165 and VEGF121 regulates vessel morphology in vitro. Fibrin bead assays were established at various VEGF165 and VEGF121 concentrations between 0 ng/ml and 35 ng/ml in the presence of SFs. Sprouts were quantified at Day 7. Data represent one experiment. Similar results were obtained in three similar experiments. Values represent mean ± sem. A, Sprouts per bead. B, Average sprout length. C, Vessel shape index. D, Vessel morphology at 2.5 ng/ml of VEGF165. E, Vessel morphology at 15 ng/ml of VEGF165. Scale bars represent 50 μm.

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