Figure 1

(a) Gross photograph of a uterus (case 1) involved by a PSTT. A 3.0 cm round tumour mass involves the endometrium and myometrium. (b) Microscopic features of PSTT (case 1) showing sheets of intermediate trophoblasts characterized by large cells with abundant cytoplasm and pleomorphic nuclei, permeating through the adjacent myometrium. (c) CGH profile of PSTT (case 1), showing chromosomal gain involving the chromosomal region at 21q21. (d) CGH profile of PSTT (case 2) showing chromosomal gains involving the chromosomal regions at 19p13.2, 21q11–21, and 22q12.