Table 1 Caspase-3 overexpression status in HCCs compared to patient and tumor characteristics

From: Overexpression of caspase-3 in hepatocellular carcinomas

Characteristic

Total

Caspase-3 Overexpression

P-value

 

(n=47)

Absent (n=20)

Present (n=27)

 
 

#

% (#)

% (#)

 

Age (years)±s.d.

61.6±13.4

64.3±12.6

59.6±13.8

NSa

Gender

    

 Female

19

37 (7)

63 (12)

NS

 Male

28

46 (13)

54 (15)

 

α-fetoprotein

    

 <40

12

58 (7)

42 (5)

0.01b

 >40

19

16 (3)

84 (16)

 

 Not available

16

63 (10)

37 (6)

 

Hepatitis

    

 Absent

25

44 (11)

56 (14)

NS

 Present

22

41 (9)c

59 (13)d

 

Cirrhosis

    

 Absent

24

37 (9)

63 (15)

NS

 Present

23

48 (11)

52 (12)

 

Tumor stage

    

 2

16

37 (6)

63 (10)

NS

 3

17

47 (8)

53 (9)

 

 4

14

43 (6)

57 (8)

 

Vital status

    

 Alive

20

45 (9)

55 (11)

NS

 Dead

27

41 (11)

59 (16)

 

Follow-up (months)±s.d.

29.0±29.1

35.1±32.4

24.6±26.0

NSe

  1. aNS, not significant.
  2. bα-fetoprotein <40 vs >40.
  3. cHepatitis B viral infection (n=3), hepatitis C viral infection (n=2), alcoholic liver disease (n=4), and hepatitis B viral infection and alcoholic liver disease (n=1).
  4. dHepatitis B viral infection (n=5), hepatitis C viral infection (n=5), alcoholic liver disease (n=3).
  5. By Kaplan and Meier method, log-rank statistic.