Table 1 Associations between number of chromosomal alterations and clinicopathologic factors in gastric cancer (P: Student's t-test)

Clinicopathologic parameters		Number of patients	Gain	P-value	Loss	P-value	Total	P-value
Age	<69 y.o.	50	7.58±3.47		4.50±3.00		12.06±5.79
	≧69 y.o.	52	8.34±3.40	P=0.26	4.50±2.99	P=0.99	12.84±4.99	P=0.46
Gender	Male	74	8.29±3.45		4.39±2.90		12.67±5.40
	Female	28	7.10±3.29	P=0.12	4.78±3.21	P=0.55	11.89±5.39	P=0.51
Location	Antrum	31	8.12±3.48	A/B P=0.20	4.72±3.09	A/B P=0.05	12.87±5.42	A/B P=0.05
	Body	36	7.02±3.55	A/C P=0.41	3.44±2.24	A/C P=0.42	10.44±4.48	A/C P=0.35
	Cardia	35	8.80±3.13	B/C P=0.03	5.37±3.28	B/C P=0.005	14.17±5.66	B/C P=0.003
Diameter	<65 mm	58	7.62±3.48		4.13±2.87		11.75±5.30
	≧65 mm	44	8.43±3.36	P=0.24	4.97±3.09	P=0.16	13.38±5.41	P=0.13
Grade	1, 2	53	8.83±3.13		5.17±3.14		13.98±5.22
	3	49	7.04±3.54	P=0.008	3.77±2.64	P=0.018	10.81±5.12	P=0.002
CSR	med, int	83	8.37±3.20		4.80±3.10		13.18±5.22
	sci	19	6.21±3.96	P=0.01	3.15±1.92	P=0.03	9.31±5.10	P=0.004
pT	1	9	6.66±3.31		2.55±1.33		9.22±4.11
	2, 3, 4	93	8.09±3.44	P=0.23	4.68±3.03	P=0.04	12.77±5.41	P=0.05
pN	(+)	73	8.17±3.51		4.83±3.02		13.00±5.38
	(−)	29	7.44±3.24	P=0.33	3.65±2.75	P=0.07	11.10±5.25	P=0.10
pM	(+)	10	7.61±2.95		4.00±2.55		11.61±4.55
	(−)	92	8.02±3.51	P=0.69	4.57±3.04	P=0.52	12.58±5.51	P=0.54
Stage	1, 2	42	8.11±3.50		4.28±3.31		12.40±5.78
	3, 4	60	7.86±3.42	P=0.71	4.65±2.91	P=0.55	12.50±5.14	P=0.93
Lymphatic invasion	(+)	89	8.06±3.44		4.62±3.02		12.68±5.36
	(−)	13	7.30±3.44	P=0.46	3.61±2.63	P=0.25	10.92±5.31	P=0.27
Venous invasion	(+)	63	8.44±3.42		4.85±2.86		13.28±5.18
	(−)	39	7.20±3.37	P=0.07	3.92±3.11	P=0.12	11.12±5.51	P=0.04

CSR: cancer–stroma relasionship, med: medullary-type, int: intermediate-type, sci: scirrhous-type, y.o: years old.

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