Table 4 Combined overexpression patterns of cyclins

From: Proliferation profile of classical Hodgkin's lymphomas. Increased expression of the protein cyclin D2 in Hodgkin's and Reed–Sternberg cells

Combined patterns

Concomitant overexpression

Mutually exclusive overexpression

Double-negative overexpression

cyclin D2/cyclin D3

23/77 cases (30%)

38/77 cases (50%)

16/77 cases (20%)

cyclin E/D-cyclins (D1 or D2 or D3)

51/83 cases (60%)

32/83 cases (40%)

0/83 cases (0%)

cyclin A/cyclin B1

72/93 cases (77%)

16/93 cases (17%)

5/93 cases (6%)

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