Table 4 Results of mutational analysis
From: Mutations in components of the Wnt signaling pathway in adenoid cystic carcinoma
Case | Subtype | Nuclear staining of β-catenin | CTNNB1 (mutation) | APC (mutation) | AXIN1 (mutation) |
|---|---|---|---|---|---|
1 | T | (−) | N | N | N |
2 | T | (−) | N | N | N |
3 | T | (−) | N | N | N |
4 | T | (−) | N | N | N |
5 | T | (−) | N | N | N |
6 | T | (−) | N | N | Pro661Leu |
7 | C | (−) | N | N | N |
8 | C | (−) | N | N | N |
9 | C | (−) | N | N | N |
10 | C | (−) | N | N | N |
11 | C | (−) | N | N | N |
12 | C | (−) | N | N | N |
13 | C | (−) | N | N | N |
14 | C | (−) | N | Arg1399Cys | N |
15 | C | (−) | N | N | Gly433Glu |
16 | C | (+) | Ile35Thr | N | Glu842Lys, Ser828Gly |
17 | S | (−) | N | N | N |
18 | S | (+) | N | 4393-4394del | N |
19 | S | (−) | N | N | Phe824Lys |
20 | S | (−) | N | N | Glu842Gly, Ser828Tyr |
