Figure 1 | Modern Pathology

Figure 1

From: Downregulation of 14-3-3σ in ovary, prostate and endometrial carcinomas is associated with CpG island methylation

Figure 1

14-3-3σ protein expression in normal and malignant urological and gynecological tissues assessed by immunohistochemistry. (a) Normal prostate tissue stained with 14-3-3σ showed positivity of the basement membrane and some epithelial cells. (b) Normal bladder stained with 14-3-3σ showed positive staining of the cytoplasm of urothelial cells. (c) A case of prostatic adenocarcinoma sigma showing strong 14-3-3σ positivity in the cytoplasm and nuclei of tumor cells. (d) Prostatic adenocarcinoma negative for 14-3-3σ. (e) A case of endometrial adenocarcinoma showing strong positivity of 14-3-3σ. The expression by tumor cells was mainly cytoplasmic. (f) Endometrial adenocarcinoma negative for 14-3-3σ.

Back to article page