Table 4 Comparisons of mean CD31 and D2-40 microvessel density, visually and image cytometrically, with immunohistochemical expression of vascular endothelial growth factor (expressed as Pearson's correlations with associated P-values)

From: Angiogenic and lymphangiogenic microvessel density in breast carcinoma: correlation with clinicopathologic parameters and VEGF-family gene expression

VEGF expression

Microvessel density technique

 

CD31

(visual)

D2-40

(visual)

CD31

(image cytometric)

D2-40

(image cytometric)

Malignant cells

0.235

(P=0.2204)

−0.29

(P=0.1333)

−0.1081

(P=0.5841)

0.1517

(P=0.4410)

Intratumoral vascular endothelium

0.275

(P=0.1574)

0.07

(P=0.7081)

0.1634

(P=0.4154)

0.1914

(P=0.3390)

Peritumoral vascular endothelium

0.493

(P =0.0170)

0.35

(P=0.1060)

0.4864

(P =0.0217)

0.6325

(P =0.0012)

  1. Significant correlations are in boldface.
  2. VEGF=vascular endothelial growth factor.