Table 6 Summary of multivariate analysis of ER-negative tumors

From: Estrogen receptor-negative breast carcinomas: a review of morphology and immunophenotypical analysis

Morphological feature

Prognostic factor

P-value

Pushing margin

Negative AR

0.043

 

Negative EGFR

0.013

 

Lymph node stage 1

0.019

 

Absence of vascular invasion

0.054

 

Premenopausal status

0.005

Lymphoid stroma

Negative GCDCP

0.006

 

Grade 3 tumor

0.012

Comedo-type necrosis

Negative AR

0.007

 

Positive CK5

0.011

 

Grade 3 tumor

0.04

 

Greater tumor size

0.09

Tumor giant cells

Positive EGFR

0.03

Squamoid differentiation

Negative P53

0.018

 

Negative AR

0.04

Spindle cell change

Negative E-cadherin

0.003

Basaloid change

Lower grade tumors

0.000