Table 1 Tryptic peptides isolated from cardiac amyloid fibrils

From: Sarcoidosis and immunoglobulin lambda II light-chain amyloidosis diagnosed after orthotopic heart transplantation: a case report and review of the literature

Lamda-light chain (residue #)

Amino-acid sequence

 

1

10

20

33–55

V-S-W-Y-Q-Q-S-P-G-T-A-P-Q-L-M-I-Y-E-V-N-N-R-P…

67–88

S-G-N-T-A-S-L-T-I-S-G-L-Q-A-E-D-E-A-D-Y-Y-C…

111–129a

A-A-P-T-V-T-L-F-P-P-S-S-E-E-L-Q-A-N-K

130–149b

A-T-L-V-C-L-I-S-D-F-Y-P-G-A-V-T-V-A ( )K

  1. aThe lambda constant region is MCG (+) with Thr114.
  2. bNo amino acid was identified at residue 148 which is usually Trp.