Table 2 Summary of Ki-67, p21, and fatty acid synthase immunoreactivity
From: Spitz nevi and atypical Spitz nevi/tumors: a histologic and immunohistochemical analysis
Ki-67 % nuclear positivity | p21 % nuclear positivity | Fatty acid synthase (0–3+) positivity | |||||||
|---|---|---|---|---|---|---|---|---|---|
N | Mean (s.d.) | 95% CI | N | Mean (s.d.) | 95% CI | N | Mean (s.d.) | 95% CI | |
Conventional nevi | 19 | 0.53 (0.61) | 0.23–0.82 | 19 | 0.21 (0.54) | 0.05–0.47 | 19 | 0.21 (0.42) | 0.01–0.41 |
Spitz nevi | 26 | 5.04 (2.46) | 4.05–6.03 | 26 | 46.50 (21.37) | 37.87–55.13 | 26 | 0.46 (0.65) | 0.20–0.72 |
Atypical Spitz nevi | 10 | 10.0 (4.16) | 7.02–12.98 | 8 | 49.25 (28.10) | 25.76–72.74 | 8 | 1.56 (0.73) | 1.00–2.11 |
Malignant melanoma | 18 | 36.83 (25.82) | 23.99–49.67 | 18 | 27.50 (18.03) | 18.53–36.57 | 18 | 2.28 (0.46) | 2.05–2.51 |
