Table 2 Immunoreactivity for various markers in the uterine leiomyomata and normal myometrium

From: Expression profile of tuberin and some potential tumorigenic factors in 60 patients with uterine leiomyomata

Markers

Panel

No. cases a

Leiomyomata

Myometrium

P-value

   

Mean

s.d.

Mean

s.d.

 

Tuberin

A

54

0.644231

0.042228

0.995327

0.044576

5.25E-08

Hamartin

A

54

0.754717

0.045366

0.721698

0.040623

0.589999

Phosphatidylinositol 3-kinase

B

54

0.717374

0.053359

0.542933

0.049989

0.084125

AKT kinase

B

53

0.941767

0.041201

0.835554

0.042245

0.315237

Insulin-like growth factor receptor β

B

52

1.174757

0.054798

1.029126

0.043326

0.039273

Insulin-like growth factor 1

B

56

1.238739

0.055482

0.968468

0.047365

0.000285

Glucocorticoid receptor

C

55

0.363636

0.041922

1.077273

0.046232

1.04E-23

Estrogen receptor

C

51

1.005007

0.069123

1.217822

0.069103

0.031865

Progesterone receptor

C

55

1.444954

0.06466

1.634259

0.059238

0.033197

Amplified in breast cancer 1

C

56

1.991071

0.074433

1.687500

0.066855

0.002817

Steroid receptor cofactor 1

C

55

2.213636

0.05596

2.004545

0.065420

0.016918

Glucocorticoid receptor interacting protein 1

C

54

0.546296

0.038479

0.291667

0.028634

3.1E-07

Epidermal growth factor receptor

D

58

0.939130

0.051644

1.017241

0.058130

0.319419

High-mobility group protein gene A2

D

55

0.786760

0.058145

0.212235

0.050288

0.007576

CD24

D

50

1.546447

0.037441

0.786955

0.039845

1.77E-05

Ki-67

D

50

6.737374

0.908305

2.275510

0.231882

4.63E-06

  1. aAmong total 60 cases, those cases with well-preserved cores for both myometrium and leiomyomata cores were counted.
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