Table 2 Concurrent methylation of tumor suppressor genes in cholangiocarcinoma

From: Promoter methylation profiles of tumor suppressor genes in intrahepatic and extrahepatic cholangiocarcinoma

Number of TSG

CC (%) (72)

ICC (%) (36)

ECC (%) (36)

0 TSG

15.3 (11)

16.7 (6)

13.9 (5)

1 TSG

2.7 (2)

2.7 (1)

2.7 (1)

2 TSGs

11.2 (8)

13.9 (5)

8.3 (3)

3 TSGs

19.4 (14)

16.7 (6)

22.2 (8)

≥4 TSGs

51.4 (37)

50.0 (18)

52.9 (19)

  1. Absolute case numbers are included within parentheses. Abbreviations: TSG—tumor suppressor gene; CC—cholangiocarcinoma; ICC—intrahepatic cholangiocarcinoma; ECC—extrahepatic cholangiocarcinoma.