Table 5 Pattern of p16INK4a immunostaining in grades of CIN in adolescent cervical biopsies that were high-risk HPV positive

From: Human papillomavirus genotyping and p16INK4a expression in cervical intraepithelial neoplasia of adolescents

CIN grade

p16INK4a (+)/high-risk HPV (+)

Patchy

Diffuse basal

Diffuse full thickness

CIN 1

7/18 (39%)

5 (28%)

2 (11%)

0

CIN 2

33/33 (100%)

12 (36%)

9 (27%)

12 (36%)

CIN 3

38/38 (100%)

5 (13%)

7 (18%)

26 (68%)

  1. Abbreviations: see Table 2.
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