Table 5 Stage I patients only: the Cox regression analysis estimated prognostic value by hazard ratios (HR) and 95% CI* for relapse-free survival and disease-specific survival

From: Reduced PTEN expression predicts relapse in patients with breast carcinoma treated by tamoxifen

Variable **

Relapse-free survival

Disease-specific survival

 

P***

HR

95% CI

P***

HR

95% CI

PTEN (per score point)

<0.0001

0.384

0.237–0.622

0.032

0.577

0.349–0.953

Age (per year)

0.055

1.038

0.999–1.077

0.193

1.031

0.985–1.079

Tumor size (per cm)

0.741

1.170

0.460–2.975

0.702

1.255

0.392–4.015

Tumor grade (per point)

0.098

0.529

0.249–1.124

0.211

0.560

0.226–1.390

ER-α (per score point)

0.705

1.088

0.702–1.687

0.664

1.129

0.653–1.954

PR (per score point)

0.509

0.874

0.586–1.304

0.073

0.608

0.353–1.048

Her-2 (per score point)

0.005

1.585

1.153–2.179

0.025

1.567

1.058–2.319

  1. *CI denotes confidence interval.
  2. **Constant or linearly dependent covariates stage=1 and axillary LN metastases=0 excluded from analysis.
  3. ***P-values were computed from Wald statistics.
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