Table 2 Bone marrow pathology

From: Diffuse large B-cell lymphoma with distinctive patterns of splenic and bone marrow involvement: clinicopathologic features of two cases

 

Cellularity

Eryth

Grans

Megs

Lymphoma H&E

Lymphoma IHC

Lymphoma pattern

Pt 1

INC (75%)

INC

NL

NL

5%

20%

Intrasinusoidal & Interstitial

Pt 2

INC (65%)

INC

NL

INC

10%

20–30%

Intrasinusoidal & Interstitial

  1. Pt 1, patient 1; Pt 2, patient 2; INC, increased; NL, normal; Eryth, erythropoiesis; Grans, granulopoiesis; megs, megakaryopoiesis; lymphoma H&E, percentage marrow involvement by lymphoma as estimated from morphology; lymphoma IHC, percentage marrow involvement by lymphoma as estimated from CD20 immunoperoxidase stain.
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