Table 1 Immunohistochemical features of primary systemic nodal/extranodal and primary cutaneous ALCL, and the ALK+ diffuse large B-lineage lymphoma

From: Extra copies of chromosome 2 are a recurring aberration in ALK-negative lymphomas with anaplastic morphology

 

Total numbers of patients

CD30 positive

CD15 positive

ALK positive

EMA positive

TIA-1 and/or granzyme B positive

T-cell antigens positive

Other

Primary systemic nodal/extranodal ALCL

15

15/15

0/9

10/15

3/8

11/15

13/15

Not applicable

Primary cutaneous ALCL

6

6/6

Not available

0/6

Not available

2/5

6/6

Not applicable

ALK+ diffuse large B-lineage lymphoma

1

0/1

Not available

1/1

Not available

Not available

0/1 (CD3−CD4− CD5−CD8−)

CD138+, cytoplasmic IgG+, IgA−, IgM−, λ+, κ−, CD20−, CD79a−