Table 3 Association between tight junction protein expression and tumor grade

From: Claudin-1 is a strong prognostic indicator in stage II colonic cancer: a tissue microarray study

 

Tumor differentiation

P-value*

Well

Poorly

Claudin-1

 Absent/lowa

23

8

0.051

 Normal/elevateda

85

11

 

Claudin-4

 Absent/low

41

11

0.11

 Normal/elevated

66

8

 

Occludin

 Absent/low

43

12

0.062

 Normal/elevated

64

7

 

ZO-1

 Absent/low

56

15

0.028

 Normal/elevated

52

4

 
  1. aAbsent/low (0 or 1+ staining), normal/elevated (2+ or 3+ staining).
  2. *P-value (χ2 test).