Table 3 Genes showing differential expression in prostate cancer vs normal cells

From: Combined laser capture microdissection and serial analysis of gene expression from human tissue samples

Tag

 

Cancer

Normal

Unigene

GENE

Description

P-value

GTGAAACCCC

*

57

37

268049

HSPC031(CSF2RA)

Hypothetical protein HSPC031

0.026556

CCCATCATCC

 

5

0

306122

GPSN2

Glycoprotein, synaptic 2

0.031748

GGGTTTTTAT

 

5

0

74497

NSEP1

Nuclease sensitive element binding protein 1

0.031748

AAGGAGATGG

*

59

40

164170

VRP(RPL31)

Vascular Rab-GAP/TBC-containing(ribosomal protein L31)

0.037452

TGTGATCAGA

 

15

6

107476

ATP5L

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g

0.040422

ACTTTTTCAG

 

0

6

171495

RARB

Retinoic acid receptor, beta

0.007641

TCCATACACC

 

0

5

89497

LMNB1

Lamin B1

0.01533

TAAAAAAAAA

*

2

9

379466

UBE2A

Ubiquitin-conjugating enzyme E2A (RAD6 homolog)

0.018782

TTTAGGTAAA

 

1

7

76698

SERP1

Stress-associated endoplasmic reticulum protein 1

0.01909

GTGTATATTG

 

3

10

42251

MGC10067

Hypothetical protein MGC10067

0.027921

AAGGCAATTT

*

0

4

278479

TSPYL

TSPY-like

0.030758

AGCCCTACAG

 

0

4

   

0.030758

AGTTAAATTA

 

0

4

   

0.030758

GACACAGGCA

*

0

4

143641

LRP3

Low-density lipoprotein receptor-related protein 3

0.030758

GAGAAATGGT

 

0

4

   

0.030758

GATTCGTAAG

 

0

4

   

0.030758

GTGGCTGGTA

 

0

4

   

0.030758

TATTATTCCA

 

0

4

   

0.030758

TGTATATCGT

 

0

4

79123

KIAA0084

KIAA0084 protein

0.030758

GGCCCTACAA

 

1

6

79058

SUPT4H1

Suppressor of Ty 4 homolog 1 (S. cerevisiae)

0.034469

  1. According to Monte Carlo simulation, 20 transcripts revealed differential expression at significant different levels (P<0.05); 15 of these were downregulated in prostate cancer cells, whereas five genes were upregulated in cancer cells. Six tags had no matched gene entries. The tags matching with more than one gene are marked with an asterisk. UID, Unigene identification number.