Figure 1
From: E-cadherin alterations in atypical lobular hyperplasia and lobular carcinoma in situ of the breast
An atypical lobular hyperplasia lesion from our collection before and after laser-capture microdissection. (a) A section containing atypical lobular hyperplasia, stained with hematoxylin, before microdissection by the laser-capture microdissection technique. (b) The tissue remaining on the slide following microdissection of the lesion. Using laser-capture microdissection we could maintain the purity of the lesions, with only 15–20% contamination by non-neoplastic cells (intermediate power, × 20).
