Figure 1
From: Predominance of high-grade pathway in breast cancer development of Middle East women

Overview of an H&E-stained breast cancer TMA section (a). Examples of HER2 nonamplified (b) and amplified breast tumors (c). The tumor in panel b contains one to four centromere 17 and one to three HER2 gene signals per cell. The cancer cells in panel c show two centromere 17 and clusters of HER2 gene signals in cancer nuclei.