Table 1 Summary of XIAP staining in malignant and benign body cavity effusions and washes
From: Immunocytochemical detection of XIAP in body cavity effusions and washes
Case type (primary) | No. of cases (type of fluid) | Positive for XIAP | Staining intensity (0 to ++++) | % of XIAP + cases | Comments |
|---|---|---|---|---|---|
Ovarian | 13 (6P+6A+1PW) | 13 | + to ++++ | 100 | Mostly strong |
Lung | 11 (10P+1PC) | 9 | + to ++++ | 82 | Mostly strong in positive cells |
Breast | 13 (11P+2A) | 6 | + to +++ | 46 | Not as strong as ovarian/lung |
Gastric | 7 (5P+2A) | 4 | + to +++ | 57 | Two cases from same patient |
Colon | 4 (1P+2A+1PW) | 0 | — | 0 | |
Pancreas | 3 (2P+1A) | 2 | + to +++ | 67 | |
Gall bladder | 1 (1A) | 1 | ++ to +++ | 100 | |
Fallopian tube | 3 (1A+2PW) | 1 | + to +++ | 33 | |
Endometrial | 7 (1P+1A+5PW) | 6 | + to ++++ | 86 | |
Mesothelioma | 5 (4P+1A) | 4 | + to ++++ | 80 | |
Carcinoma NOS | 5 (5P) | 5 | +++ to ++++ | 100 | |
Hematopoietic malignancies | 9 (9P) | 3 | + to ++ | 33 | Weak stain with Golgi-like distribution seen in rare cells of MM and two NHL cases |
Negative | 35 (28P+5A+2PW) | 2 | + to ++ | 6 | Usually negative; histiocytes positive in rare cases |
Summary | Total=116 (81+35) (82P+22A+11PW+1PC) | 56 | 66.7% (54/81) malignant cases are positive for XIAP |
