Table 4 Correlation of FOXP1 immunostaining patterns with histopathological and molecular variables

From: Loss of expression and nuclear/cytoplasmic localization of the FOXP1 forkhead transcription factor are common events in early endometrial cancer: relationship with estrogen receptors and HIF-1α expression

Parameter

Nuclear FOXP1

Cytoplasmic FOXP1

 

Neg

Low

High

P-value

Neg

Low

High

P-value

Myoinvasion

        

 <1/2

34

3

6

0.10

17

17

9

0.02

 >1/2

24

9

6

 

7

14

18

 

Grade

        

 1

48

8

10

0.42

18

29

19

0.06

 2–3

10

4

2

 

6

2

8

 

ER-α

        

 Neg

49

11

5

0.002

20

27

18

0.13

 Pos

9

1

7

 

4

4

9

 

PgR

        

 Neg

48

11

7

0.08

19

27

20

0.45

 Pos

10

1

5

 

5

4

7

 

HIF-1α

        

 Low

30

7

5

0.70

18

15

9

0.01

 High

28

5

7

 

6

16

18

 

HIF-2α

        

 Low

51

9

8

0.14

22

27

19

0.09

 High

7

3

4

 

2

4

8

 

VEGF

        

 Low

31

9

8

0.31

15

16

16

0.69

 High

27

3

4

 

9

15

11

 

VD

        

 Low

30

4

7

0.41

14

11

16

0.12

 High

28

8

5

 

10

20

11

 
  1. Bold figures show statistically significant values.
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