Figure 5

Sebaceous carcinoma, low grade. Higher power microscopy of the same lesion illustrated in Figure 4 shows a dominant component of germinative epithelia within tumor lobules (a) that do not show slit-like retraction of stroma, and are thus dissimilar from the tumor nests in a sebaceous epithelioma. At high-power microscopy (b), the germinative epithelia are shown to have cytologic features of malignant neoplasia by virtue of irregularly thickened chromatinic rims and coarse, spiculated chromatin patterns.