Figure 4
From: Prognosticators of melanoma, the melanoma report, and the sentinel lymph node
Tumor-infiltrating lymphocytes: Depicted are the two patterns of tumor-infiltrating lymphocytes which would be designated as ‘brisk’ and which would be a positive prognostic sign. In the left panel, lymphocytes diffusely infiltrate the melanoma mass and break up neoplastic melanocytes into groups and single cells. In the right half of the panel, tumor-infiltrating lymphocytes surround 90% of the peripheral margin of the melanoma nodule. Either of these two patterns constitutes a ‘brisk’ lymphocytic infiltrate.
