Figure 7
From: Prognosticators of melanoma, the melanoma report, and the sentinel lymph node

Angioinvasion: Although vascular invasion emerges as a powerful negative prognostic variable only in larger sample sizes, its presence is nonetheless an ominous sign and should be reported. (a) Shows neoplastic epithelioid melanocytes within the lumen of a venule. Their melanocytic character is confirmed by immunohistochemistry with a Melan-A antibody (b).