Figure 1 | Modern Pathology

Figure 1

From: The Akt pathway in human breast cancer: a tissue-array-based analysis

Figure 1

Diagrammatic representation of the Akt pathway. RTK—receptor tyrosine kinase, EGFR—epidermal growth factor receptor, IGF-1—insulin-dependent growth factor, PIP2/3—phosphatidylinositol 4,5-/3,4,5-phosphate, PI3K—phosphatidylinositol 3-kinase, PDK1—3-phosphoinositide-dependent protein kinase-1, GSK3—glycogen synthase kinase-3β.

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